Research

STRATEGY FOR THE DEVELOPMENT OF SCIENTIFIC RESEARCH

The administration, the educational unit, the human resources management department, and the quality assurance services make up the teaching university’s structure.

Objectives

The research development strategy of Bau International University has the following primary objectives:

  • Development of the quantity and calibre of scientific research conducted at the Teaching University; augmentation of higher education institutions’ research capacity; augmentation of the Teaching University’s academic staff’s research capacity;
  • Encouraging transparency, objectivity, and ethics in research.
  • Carrying out studies that promote health improvement on a local, regional, national, and international level;
  • Creation of interdisciplinary studies and fortifying the connections between the biological and medical sciences;
  • Understanding the potential for commercialization and the applicability of research;
  • Putting into practice basic and applied research, incorporating it into educational initiatives, and fostering a close relationship between them;
  • Incorporating findings from applied research into clinical practice;
  • Ensuring that research activities are sustained;
  • Forming close ties with professional associations, societies, and research;
  • Research internationalisation and securing a position in the global scientific community;

TASKS

The Teaching University has established the following tasks in order to fulfil the objectives of the strategy:

 

  • Bolstering academic staff research support systems, specifically assisting academic staff in securing, preparing, and carrying out national and international research projects; support for the planning and coordination of the activities included in the University’s internal research grant programmes for faculty members;
  • Communicating with professional associations and scientific research centres;
  • Establishing and supervising collaborative research initiatives with regional and global academic institutions
  • Train academic staff members to become more proficient in scientific research
  • Growth in the quantity and scope of research endeavours
  • Deciding which research directions are most important;
  • Organisational assistance in putting the scientific research into practice;
  • Identifying the range of policies that support scientific research;
  • Creation of research funding mechanisms at universities;
  • Bolster academic staff research support systems;
  • Expand the scope and quantity of research events (symposia, seminars, and conferences);
  • Increased support for student research and the incorporation of scientific research into educational initiatives;
  • Participation in cooperative research projects and cooperation with foreign researchers;
  • Involving outside specialists in the process of discussing and evaluating research papers;
  • Application of academic integrity, ethics, and research culture standards;
  • Putting in place a system for assessing the calibre of research projects and productivity metrics for research;
  • Openness in study findings and establishment of a regular public reporting system;
  • Expand university research’s potential for commercialization.

PRIORITY DIRECTIONS OF SCIENTIFIC RESEARCH

IMMUNOHEMATOLOGICAL STUDIES

Within the internal grant project’s parameters:

An investigation was conducted on newborns with alloimmune thrombocytopenia caused by immunoglobulin G-stimulated platelet surface antigens, specifically HPA 1a and HPA 5b. Acute thrombocytopenia and intracranial rupture in neonates are frequently caused by these kinds of thrombocytopenias. Because it is the foundation of contemporary research and is not conducted in Georgia, this study is especially important. The HPA 1a antigen is responsible for over 75% of neonatal alloin allomin thrombocytopenias in the Caucasus population. In addition to studying antigen presence and antibody-mediated immunosensitization, HPA and HLA genotyping will also be conducted.

For many years, the teaching institution has collaborated on research projects with BSU and the Medina Clinic. Specifically, the identification of blood types in infants who have experienced aggravation in the past and the investigation of the immunosensitization index in expectant mothers due to the ABO, Rh, and Kell systems.

Students are participating in the research as well as publications that have already been published in this area.

An epidemiological investigation of epilepsy in the Ajara population

Within the internal grant project’s parameters:

Following the preliminary investigation, the materials processed will allow for the differentiation and examination of further parameters, specifically:

The prevalence of both lifetime and active epilepsy

Epilepsy-associated mortality metrics

deciding whether to treat epileptic patients with antiepileptic medication (inadequate treatment).

Calculating the disease’s mortality and morbidity rates will be feasible through additional processing of the research data. Determining the disease’s economic burden for a particular area will also be crucial.

It will be feasible to conduct physiological research as part of this study. organising research projects related to the physiology of sleep as well.

Research on anticonvulsant medications, both novel and old, can be done in labs and in cooperation with pharmaceutical corporations.

Close scientific ties with the Institute of Neurology and Neuropsychology, which are actively engaged in numerous international scientific projects, will be conceivable within the scientific direction.

The study of spatial memory formation falls under the purview of an internal grant project that aims to evaluate the allocentric system of spatial memory in urban and rural children aged 3 to 5 years of typical development. The assessment is based on neuropsychological behaviour analysis of the children’s performance during a spatially delayed task under various conditions. Additionally, the study will examine the effects of prolonged use of digital technologies on the children.

The study’s findings suggest that the study’s geographic scope be increased in the future. We also intend to use electrospectrography (Neurofeedback & QEEG) tools to assess the relationship between attention deficit and spatial memory deficit.

Investigation of Epigenetic and Autophagic Ageing Molecular Markers

Georgia stands out for having a high population rate, which is dependent on a variety of factors, particularly in highland Ajara. Scientists from Batumi Shota Rustaveli University who specialise in the natural sciences and health have long been conducting research in this area.

Research in this area, in collaboration with BSU and the University Hospital of Bonn, is one of the teaching university’s top priorities. The grant project has already been submitted, with Bonn University Hospital serving as the supervisor. The goal of this study is to gather proof that, in the context of epigenetic influences on ageing in the Georgian population, autophagy plays a significant role.

Investigations on microbiology

The teaching university also intends to conduct research in the area of microbiology, looking at topics such as mycoplasma and ureaplasma antibiotic resistance, as well as the microflora of the vagina during the perimenopause.

Research in this area, in collaboration with BSU and the University Hospital of Bonn, is one of the teaching university’s top priorities. The grant project has already been submitted, with Bonn University Hospital serving as the supervisor. The goal of this study is to gather proof that, in the context of epigenetic influences on ageing in the Georgian population, autophagy plays a significant role.

Research on personalised medicine and pharmacogenomics

Individual patient orientation, which suggests a unique approach to each patient in the prevention or treatment of the disease, taking into account the patient’s genetics, living environment, and lifestyle, is the foundation of personalised medicine. The investigation of the cytochrome P450 (CYPs) enzyme’s genetic polymorphism is one of the contemporary research methods in this area. These enzymes are encoded by 57 genes that have been found so far. Any of them can have mutations that alter their functionality, which can alter how each person reacts to medications. When providing individualised care, genetic polymorphism of these enzymes should be taken into account.

Pharmacogenetic polymorphism is already present if a mutational allele is found in at least 1% of the population. To prevent unneeded toxicity and treatment complications, a personalised approach to drug selection and dosage is crucial. For instance, only 2% of liver tissue expresses CYP 2D6, despite the fact that this enzyme is involved in the metabolism of hundreds of medications, such as beta-blockers, opiates, antidepressants, and neuroleptics. The inability of about 10% of the Caucasian population to properly metabolise these medications results in side effects.Given the foregoing, choosing the medication on your own will be crucial in this situation.

STEM CELL RESEARCH

The detrimental effects of metabolic syndrome are growing, as are the effects of metabolic syndrome on health. Insulin resistance may be linked to adiposity because adipokines, which are secreted by adipose tissue, affect insulin sensitivity. The aim of the study is to assess the impact of mesenchymal stem cell transplantation using the fructose SDR model, apelin, and SIRT1 gene expression. These studies may have therapeutic applications and present fresh approaches to the management of insulin resistance.

Two students will be able to work on partner research in partner higher education laboratories as part of this joint project with Bahçeşehir University.

Pharmacogenetic polymorphism is already present if a mutational allele is found in at least 1% of the population. To prevent unneeded toxicity and treatment complications, a personalised approach to drug selection and dosage is crucial. For instance, only 2% of liver tissue expresses CYP 2D6, despite the fact that this enzyme is involved in the metabolism of hundreds of medications, such as beta-blockers, opiates, antidepressants, and neuroleptics. The inability of about 10% of the Caucasian population to properly metabolise these medications results in side effects.Given the foregoing, choosing the medication on your own will be crucial in this situation.

SETTING UP A GMP STEM CELL LABORATORY

The detrimental effects of metabolic syndrome are growing, as are the effects of metabolic syndrome on health. Insulin resistance may be linked to adiposity because adipokines, which are secreted by adipose tissue, affect insulin sensitivity. The aim of the study is to assess the impact of mesenchymal stem cell transplantation using the fructose SDR model, apelin, and SIRT1 gene expression. These studies may have therapeutic applications and present fresh approaches to the management of insulin resistance.

Two students will be able to work on partner research in partner higher education laboratories as part of this joint project with Bahçeşehir University.

Pharmacogenetic polymorphism is already present if a mutational allele is found in at least 1% of the population. To prevent unneeded toxicity and treatment complications, a personalised approach to drug selection and dosage is crucial. For instance, only 2% of liver tissue expresses CYP 2D6, despite the fact that this enzyme is involved in the metabolism of hundreds of medications, such as beta-blockers, opiates, antidepressants, and neuroleptics. The inability of about 10% of the Caucasian population to properly metabolise these medications results in side effects.Given the foregoing, choosing the medication on your own will be crucial in this situation.